In this webinar, Harm Tiddens will discuss the relation between structural and functional abnormalities of the lung and how this can impact upon the deposition pattern and efficacy of inhaled antibiotics. He will further present the learnings of his research group’s computational fluid dynamic modelling studies and explain why the expectation that inhaled antibiotics result in high concentrations in the lung is unfortunately a misconception.
Webinar: Assay development for measuring antibiotic accumulation in Gram-negative bacteria
In this webinar, Anand Anandkumar and Kamini Walia will discuss: – Why is India one of the hotbeds of the AMR problem? Latest statistics of growing drug resistance etc. – Initiatives of the Indian Government to curb the AMR problem – Antimicrobial R&D landscape in India – a vibrant ecosystem supporting innovation in AMR diagnosis, prevention and therapeutics – Fledgling antimicrobial clinical trial networks – could trials out of India play a significant role in gaining global regulatory approvals? – Changing regulatory environment to enable accelerated approvals for antimicrobial products
Webinar with Markus Zeitlinger, Head of Department of Clinical Pharmacology, Medical University of Vienna (Austria) on the clinical development of antimicrobials – Phase 1 development challenges.
In this webinar, Vincent H. Tam will present on his work looking at studying PK/PD in fixed-dose beta-lactam/beta-lactamase (BL/BLI) inhibitor combinations. Topics discussed will include:
– Understanding the inherent challenges associated with PK/PD of BL/BLI combinations
– Demonstrating new approaches to gain useful insights from preclinical PK/PD models
In this webinar, Shampa Das will give an overview of her work in studying the probability of target attainment for dose selection. Topics discussed will include: – An overview of what is meant by the probability of target attainment (PTA) – How it is calculated and what data is used for this – How PTA is used for decision making during drug development The presentation will be followed by a Q&A session.